If you are reading this, you likely already know how exhausting depression can be. It is more than just feeling sad; it is a heavy, persistent fog that drains your energy, steals your joy, and makes even the simplest daily tasks feel insurmountable.

IV ketamine depression treatment session at AlphaOmega Wellness in Greenwood Indiana - patient reclining comfortably during ketamine infusion for depression relief

Perhaps you have tried multiple antidepressants, spent hours in talk therapy, and made lifestyle changes, only to find that the heavy cloud of depression remains. This is known as treatment-resistant depression, and if you are experiencing it, you are not alone — and it is not your fault.

At AlphaOmega Wellness in Greenwood, Indiana, we offer a scientifically proven, fast-acting alternative: IV Ketamine Therapy. Led by Dr. Dee Bonney, a board-certified physician who has personally experienced the life-saving benefits of this treatment, our clinic provides a safe, compassionate environment for you to finally find the relief you deserve.

Why Traditional Antidepressants Often Fall Short

Traditional antidepressants work by increasing the levels of certain neurotransmitters in the brain, such as serotonin or dopamine. While these medications can be effective for some, they come with significant drawbacks for many others:

  • Delayed Onset: SSRIs can take 4 to 8 weeks to build up in your system before you feel any noticeable improvement. When you are suffering from severe depression, waiting two months for relief feels like an eternity.
  • Low Efficacy Rates: Studies show that up to 30% of patients do not respond adequately to traditional antidepressants, and many more experience only partial relief.
  • Unwanted Side Effects: Weight gain, emotional blunting, insomnia, and sexual dysfunction are common side effects that cause many patients to abandon their medication.

If you have tried two or more antidepressants without adequate success, it is time to look at a different approach.

How IV Ketamine Therapy Works for Depression

Ketamine works entirely differently than traditional psychiatric medications. Instead of targeting serotonin, ketamine targets the glutamate system in the brain. Glutamate is the most abundant excitatory neurotransmitter and plays a crucial role in neuroplasticity — the brain’s ability to adapt, heal, and form new connections.

Chronic depression causes physical changes in the brain, literally shrinking the synaptic connections between neurons. This is why depression feels like being stuck in a rigid, negative thought loop. When administered intravenously in a controlled medical setting, ketamine triggers a rapid release of glutamate, stimulating the growth of new synapses and effectively rewiring the brain to repair the damage caused by chronic stress and depression.

Rapid, Measurable Results at AlphaOmega Wellness

  • Rapid Relief: Many of our patients report a noticeable lifting of their depressive symptoms within hours or days of their first infusion — not weeks or months.
  • High Success Rate: At AlphaOmega Wellness, we see a 65% to 70% reduction in depression and anxiety scores within just three to four weeks of starting our treatment protocol.
  • Breaking the Cycle: Ketamine helps quiet the Default Mode Network (DMN) in the brain, which is responsible for rumination and negative self-talk, allowing you to finally break free from the cycle of depression.

What to Expect During Your IV Ketamine Treatment

  1. Comprehensive Medical Consultation: Your journey begins with a thorough evaluation by Dr. Dee Bonney, MD and Megan Bonney, PMHNP. We review your medical history, discuss your struggles with depression, and determine if IV ketamine is the right fit for you.
  2. The Infusion Experience: Treatments take place in our quiet, private rooms in our Greenwood clinic. The infusion lasts about 40 minutes. You will remain awake but in a deeply relaxed state. Many patients listen to calming music and wear an eye mask.
  3. Medical Supervision: Your vital signs are continuously monitored by our trained clinical staff throughout the entire process.
  4. The Protocol: For optimal, long-lasting results, the standard protocol for depression involves a series of 6 infusions administered over a 2 to 3-week period.

Is IV Ketamine Right for You?

IV Ketamine therapy is highly effective for adults who are struggling with Major Depressive Disorder, Treatment-Resistant Depression, Postpartum Depression, Bipolar Depression, or Suicidal Ideation. We serve patients from Greenwood, Indianapolis, Carmel, Fishers, and surrounding communities across Indiana.

Take the First Step Toward Healing

You do not have to live under the weight of depression forever. There is hope, and there is a path forward. Dr. Dee Bonney experienced the transformative power of this medicine firsthand, and our entire team is dedicated to helping you find that same relief.

Contact AlphaOmega Wellness today to schedule your free, confidential consultation.

Schedule My Free Consultation | Call Us: 317-300-4091