INDIANAPOLIS & GREENWOOD • PHYSICIAN-LED

IV Ketamine Therapy for PTSD in Indianapolis & Greenwood

The hypervigilance that never fully powers down. The sleep that won’t come. The sense that you left part of yourself back on a call, or in a moment you’d give anything to forget. That’s trauma living in your nervous system, not weakness. We treat it with physician-led IV ketamine plus integration, so the relief carries into real life.

5,000+

IV Infusions Performed

25+ yrs

Physician Experience

65–70%

Avg. Symptom Score Drop

4.9★

Google Rating (109+ reviews)

Symptom-score data based on AlphaOmega Wellness treatment records, 2018–2026, using PHQ-9 and GAD-7. Individual results vary.

IF THIS SOUNDS FAMILIAR

Your Brain Kept the Receipts.

You ran toward the thing everyone else ran from, or you lived through something no one should have to. Now your brain runs threat-detection around the clock.

Trauma physically changes the brain, the amygdala, hippocampus, and prefrontal cortex. This is biology, not a character flaw. And here’s the hard part: once trauma is encoded in those pathways, talking about it alone often can’t reach it, and sometimes it just makes you relive it.

SSRIs manage the surface

Standard meds can take the edge off symptoms but don’t address the neural patterns underneath the trauma.

Talk therapy can retraumatize

Approaches that require reliving the event help some people but stall or overwhelm others.

Trauma is encoded deep

Once it’s wired into neural pathways, trauma is extremely hard to reach through conscious effort alone.

Hyperarousal resists willpower

You can’t think your way out of a nervous system stuck in constant alarm. It needs a different kind of reset.

THE MECHANISM

How IV Ketamine Helps the Brain Heal From Trauma

Ketamine works on NMDA receptors and triggers BDNF, opening a window of neuroplasticity where the brain can start to reorganize on its own. The key part for trauma: you don’t have to relive it or narrate it for the shift to happen.

Ketamine opens the door. Integration helps you walk through it. Many people feel their nervous system go quiet during the infusion itself, some say for the first time in years.

No reliving required

Ketamine creates the conditions for the brain to reorganize without forcing you back into the traumatic memory.

It opens a neuroplasticity window

For days after each infusion, traumatic patterns can start to loosen their grip while the brain is primed to rewire.

It calms the nervous system fast

Many people report less hypervigilance and better sleep within the first few sessions.

A reset, not sedation

This isn’t numbing out. It’s a genuine neurological reset you can build real healing on.

WHO WE HELP

PTSD Patients We Serve

Veterans & Active Military

A respectful, no-stigma environment and veteran discounts. You served. This is care that goes beyond the usual options.

First Responders

Police, fire, EMS, dispatch. The cumulative weight of the job is real, and we offer first-responder discounts because you’ve earned better than white-knuckling it.

Complex & Childhood Trauma

When years of therapy haven’t been enough, ketamine’s neuroplasticity effect can open a genuinely new door.

Assault & Abuse Survivors

A safe, private, compassionate setting. You’re never required to detail your history beyond what’s medically necessary.

Trauma doesn’t only come from combat or violence. Accidents, medical emergencies, and sudden loss can cause PTSD that’s just as real. First responders and veterans: ask about our discounts, and see our dedicated First Responders & Veterans page.
WHAT TO EXPECT

What PTSD Treatment Actually Looks Like

1. Free consult

A safe, private conversation. You’re never asked to relive your trauma. We just see if IV ketamine is the right fit and build your plan.

2. Your protocol

Typically 6 infusions over 3 to 4 weeks, about 40 minutes each. Many describe the infusion itself as the calmest they’ve felt in years.

3. Monitored throughout

Your provider and the clinical team monitor you the entire session, in a quiet, controlled setting.

4. Integration support

We help you turn the neuroplasticity window into lasting change through journaling, somatic work, and therapy coordination.

AlphaOmega Wellness is physician-led and family-owned, founded by Dr. Dee Bonney, MD and Megan Bonney, PMHNP-BC. We accept HSA and FSA, offer first-responder and veteran discounts, and every new patient starts with a free consult.
QUESTIONS PEOPLE ACTUALLY ASK

PTSD + IV Ketamine: Your Questions

Can IV ketamine really help with PTSD?

Yes. Emerging research strongly supports IV ketamine for PTSD, including treatment-resistant cases. Unlike SSRIs, which manage symptoms, ketamine promotes neuroplasticity, helping the brain build new pathways that loosen the grip of traumatic memories. Many people report less hypervigilance, fewer flashbacks, and calmer reactivity.

How is it different from EMDR or SSRIs?

EMDR and talk therapy require consciously engaging with traumatic material, which can be slow or retraumatizing. SSRIs manage symptoms without touching the underlying patterns. Ketamine doesn’t require reliving the trauma. It creates neuroplasticity so the brain can begin reorganizing on its own.

How quickly does it work?

Many patients notice a calmer nervous system, less hypervigilance, and better sleep within 24 to 72 hours of the first infusion. The full benefit builds over the six-infusion series, and integration work amplifies and sustains it.

Is it safe for PTSD patients?

Yes. Every infusion is physician-supervised with full medical monitoring, and we screen carefully beforehand. The setting is calm, private, and comfortable.

Do you offer discounts for veterans or first responders?

Yes. We specifically offer discounts for first responders and veterans, in recognition of the weight those careers carry. Call 317-300-4091 to learn more.

How much does it cost?

It depends on the personalized plan from your free consult. We accept HSA and FSA and offer flexible payment options.

Do you treat patients from outside Indianapolis?

Yes. Patients travel from Greenwood, Carmel, Fishers, Noblesville, Westfield, Avon, Brownsburg, Plainfield, Mooresville, Southport, Bargersville, and throughout Central Indiana.

You’ve carried this long enough.

Book a free consult and we’ll tell you honestly whether IV ketamine is a fit for your PTSD. You’re never asked to relive your trauma. We’ll cover pricing, financing, HSA/FSA, and first-responder and veteran discounts. No pressure.

Serving Indianapolis, Greenwood, Carmel, Fishers, Noblesville, Westfield, Avon, Brownsburg, Plainfield, Mooresville, Southport, Bargersville and all of Central Indiana.
AlphaOmega Wellness • 1777 W. Stones Crossing Rd, Suite 140, Greenwood, IN 46143 • Call or text 317-300-4091

Medically reviewed by Dee Bonney, MD — Board-Certified Emergency Medicine, Medical Director, AlphaOmega Wellness. Last reviewed: August 2026. Meet our team →